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BDBM164497 US9066954, 440

SMILES: Cn1cc(cn1)-c1cnc2onc(c2c1)C(F)(F)c1ccc2ncccc2c1

InChI Key: InChIKey=STCFVXQDUHPTDH-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 164497   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM164497
PNG
(US9066954, 440)
Show SMILES Cn1cc(cn1)-c1cnc2onc(c2c1)C(F)(F)c1ccc2ncccc2c1
Show InChI InChI=1S/C20H13F2N5O/c1-27-11-14(10-25-27)13-8-16-18(26-28-19(16)24-9-13)20(21,22)15-4-5-17-12(7-15)3-2-6-23-17/h2-11H,1H3
PDB
MMDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
172 -9.28n/an/an/an/an/a8.027



Amgen Inc

US Patent


Assay Description
A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...


US Patent US9066954 (2015)


BindingDB Entry DOI: 10.7270/Q2N878JD
More data for this
Ligand-Target Pair