BDBM164519 US9067871, 18
SMILES Cn1cnc(c1)S(=O)(=O)NCCOc1ccc2CCC(NC(=O)C(F)(F)F)C(Cc3ccc(Cl)c(Cl)c3)c2c1
InChI Key InChIKey=UTGDZOCZGBSKMT-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 164519
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
US Patent
Abbvie Deutschland
US Patent
Affinity DataKi: <10nMAssay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
US Patent
Abbvie Deutschland
US Patent
Affinity DataIC50: <100nMAssay Description:[3H]-Glycine uptake into recombinant CHO cells expressing human GlyT1: Human GlyT1c expressing recombinant hGlyT1c5_CHO cells were plated at 20,000 c...More data for this Ligand-Target Pair