BDBM164556 US9067871, 43

SMILES NC1CCc2ccc(CNS(=O)(=O)C3CCC3)cc2C1Cc1ccccc1

InChI Key InChIKey=JYTFEYCQTQEXGG-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 164556   

TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland

US Patent
LigandPNGBDBM164556(US9067871, 43)
Affinity DataKi: <100nMAssay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland

US Patent
LigandPNGBDBM164556(US9067871, 43)
Affinity DataIC50: <1.00E+3nMAssay Description:[3H]-Glycine uptake into recombinant CHO cells expressing human GlyT1: Human GlyT1c expressing recombinant hGlyT1c5_CHO cells were plated at 20,000 c...More data for this Ligand-Target Pair
In DepthDetails US Patent