BDBM16461 2-(6-bromo-3-{[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]methyl}-1H-indol-1-yl)acetic acid::Indoleacetic Acid Inhibitor 20

SMILES OC(=O)Cn1cc(Cc2nc3cc(ccc3s2)C(F)(F)F)c2ccc(Br)cc12

InChI Key InChIKey=ZMUDJFYABJTCOO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 16461   

TargetAldo-keto reductase family 1 member A1(Homo sapiens (Human))
The Institute For Diabetes Discovery

LigandPNGBDBM16461(2-(6-bromo-3-{[5-(trifluoromethyl)-1,3-benzothiazo...)
Affinity DataIC50:  3.40E+3nMAssay Description:The activity of the test enzyme was determined spectrophotometrically by monitoring the change in absorbance at 340 nm, which is due to the disappear...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
The Institute For Diabetes Discovery

LigandPNGBDBM16461(2-(6-bromo-3-{[5-(trifluoromethyl)-1,3-benzothiazo...)
Affinity DataIC50:  52nMpH: 6.6 T: 2°CAssay Description:The activity of the test enzyme was determined spectrophotometrically by monitoring the change in absorbance at 340 nm, which is due to the disappear...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed