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BDBM164673 US9067871, 152

SMILES: Cn1cnc(c1)S(=O)(=O)NCCOc1ccc2CCC(C(Cc3ccccc3)c2c1)N1CCC(F)C1

InChI Key: InChIKey=UUNADMWTAYBZLA-UHFFFAOYNA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 164673   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycine transporter 1


(Homo sapiens (Human))
BDBM164673
PNG
(US9067871, 152)
Show SMILES Cn1cnc(c1)S(=O)(=O)NCCOc1ccc2CCC(C(Cc3ccccc3)c2c1)N1CCC(F)C1
Show InChI InChI=1/C27H33FN4O3S/c1-31-18-27(29-19-31)36(33,34)30-12-14-35-23-9-7-21-8-10-26(32-13-11-22(28)17-32)25(24(21)16-23)15-20-5-3-2-4-6-20/h2-7,9,16,18-19,22,25-26,30H,8,10-15,17H2,1H3
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
<10n/an/an/an/an/an/an/an/a



AbbVie Deutschland GmbH & Co. KG

US Patent


Assay Description
Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...


US Patent US9067871 (2015)


BindingDB Entry DOI: 10.7270/Q2HH6HV4
More data for this
Ligand-Target Pair