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BDBM165676 US9067922, 11

SMILES: Fc1ccc(NS(=O)(=O)c2ccc(Oc3cc(F)cc(F)c3)c(c2)C#N)nc1

InChI Key: InChIKey=FTYVJQWXXRYCNM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 165676   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM165676
PNG
(US9067922, 11)
Show SMILES Fc1ccc(NS(=O)(=O)c2ccc(Oc3cc(F)cc(F)c3)c(c2)C#N)nc1
Show InChI InChI=1S/C18H10F3N3O3S/c19-12-1-4-18(23-10-12)24-28(25,26)16-2-3-17(11(5-16)9-22)27-15-7-13(20)6-14(21)8-15/h1-8,10H,(H,23,24)
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 125n/an/an/an/a7.4n/a



Pfizer Inc

US Patent


Assay Description
Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...


US Patent US9067922 (2015)


BindingDB Entry DOI: 10.7270/Q2VQ31F0
More data for this
Ligand-Target Pair