BDBM16591 (4Z)-4-(2-amino-5-oxo-3,5-dihydro-4H-imidazol-4-ylidene)-4,5,6,7-tetrahydropyrrolo[2,3-c]azepin-8(1H)-one::2-amino-5-[(4Z)-8-oxo-1H,4H,5H,6H,7H,8H-pyrrolo[2,3-c]azepin-4-ylidene]-4,5-dihydro-1H-imidazol-4-one::B722657K110::CHEMBL255465::Debromohymenialdisine (DBH)::Hymenialdisine, 8::NSC607174

SMILES: NC1=NC(=O)C(N1)=C1CCNC(=O)c2[nH]ccc12

InChI Key: InChIKey=JYRJOQGKGMHTOO-UHFFFAOYSA-N

Data: 1 KI  15 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 16591   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Chk1 (Human)	BDBM16591 (B722657K110 | Hymenialdisine, 8 | CHEMBL255465 | (...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	353	n/a	n/a	n/a	n/a	7.5	30
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Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Human)	BDBM16591 (B722657K110 | Hymenialdisine, 8 | CHEMBL255465 | (...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	266	n/a	n/a	n/a	n/a	7.5	30
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Cyclin-A2/Cyclin-dependent kinase 2 (Human)	BDBM16591 (B722657K110 | Hymenialdisine, 8 | CHEMBL255465 | (...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	856	n/a	n/a	n/a	n/a	7.5	30
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Glycogen synthase kinase-3 beta (Human)	BDBM16591 (B722657K110 | Hymenialdisine, 8 | CHEMBL255465 | (...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	168	n/a	n/a	n/a	n/a	7.5	22
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3-phosphoinositide-dependent protein kinase 1 (Human)	BDBM16591 (B722657K110 | Hymenialdisine, 8 | CHEMBL255465 | (...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.83E+3	n/a	n/a	n/a	n/a	7.5	30
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RAC-alpha serine/threonine-protein kinase (Human)	BDBM16591 (B722657K110 | Hymenialdisine, 8 | CHEMBL255465 | (...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	7.5	30
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cAMP-dependent protein kinase catalytic subunit alpha (Human)	BDBM16591 (B722657K110 | Hymenialdisine, 8 | CHEMBL255465 | (...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	190	n/a	n/a	n/a	n/a	7.5	30
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Serine/threonine-protein kinase Chk2 [209-531,Q209M] (Human)	BDBM16591 (B722657K110 | Hymenialdisine, 8 | CHEMBL255465 | (...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	420	n/a	n/a	n/a	n/a	7.5	30
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Cyclin-dependent kinase 5 activator 1 (Human)	BDBM16591 (B722657K110 | Hymenialdisine, 8 | CHEMBL255465 | (...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	112	n/a	n/a	n/a	n/a	7.2	n/a
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Cyclin-dependent kinase 1 (Human)	BDBM16591 (B722657K110 | Hymenialdisine, 8 | CHEMBL255465 | (...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	250	n/a	n/a	n/a	n/a	7.2	n/a
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Glycogen synthase kinase-3 beta (Human)	BDBM16591 (B722657K110 | Hymenialdisine, 8 | CHEMBL255465 | (...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	111	n/a	n/a	n/a	n/a	7.2	n/a
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Serine/threonine-protein kinase Chk1 (Human)	BDBM16591 (B722657K110 | Hymenialdisine, 8 | CHEMBL255465 | (...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	725	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 1 (Human)	BDBM16591 (B722657K110 | Hymenialdisine, 8 | CHEMBL255465 | (...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	824	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase Chk2 (Human)	BDBM16591 (B722657K110 | Hymenialdisine, 8 | CHEMBL255465 | (...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	183	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase Chk1 (Human)	BDBM16591 (B722657K110 | Hymenialdisine, 8 | CHEMBL255465 | (...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk1 (Human)	BDBM16591 (B722657K110 | Hymenialdisine, 8 | CHEMBL255465 | (...) Show SMILES Show InChI	GoogleScholar	UniChem		659	-8.57	n/a	n/a	n/a	n/a	n/a	7.5	30
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