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BDBM166112 US9067937, 56

SMILES: CN(C)C[C@H]1CC[C@@H](CC1)Nc1c(cnc2ccc(nc12)-c1ccncc1)C(C)=O

InChI Key: InChIKey=NKCHIXRHDOVERC-UAPYVXQJSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 166112   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Maternal embryonic leucine zipper kinase (MELK)


(Homo sapiens (Human))
BDBM166112
PNG
(US9067937, 56)
Show SMILES CN(C)C[C@H]1CC[C@@H](CC1)Nc1c(cnc2ccc(nc12)-c1ccncc1)C(C)=O
Show InChI InChI=1S/C24H29N5O/c1-16(30)20-14-26-22-9-8-21(18-10-12-25-13-11-18)28-24(22)23(20)27-19-6-4-17(5-7-19)15-29(2)3/h8-14,17,19H,4-7,15H2,1-3H3,(H,26,27)/t17-,19-
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 16n/an/an/an/a7.425



OncoTherapy Science Inc

US Patent


Assay Description
MELK activity was determined in the presence or absence of compounds using fluorescein isothiocyanate-labeled (FITC-labeled) histone H3 peptide as a ...


US Patent US9067937 (2015)


BindingDB Entry DOI: 10.7270/Q2BR8QX4
More data for this
Ligand-Target Pair