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BDBM166609 3-(6-Bromo-1-methyl-1H-indol-3-yl)-4-(furo[2,3-b]pyridin-3-yl)-1H-pyrrole-2,5-dione (5i)

SMILES: Cn1cc(C2=C(C(=O)NC2=O)c2coc3ncccc23)c2ccc(Br)cc12

InChI Key: InChIKey=BAHMZNVLLWJUJB-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 166609   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycogen synthase kinase-3 beta


(Homo sapiens (Human))
BDBM166609
PNG
(3-(6-Bromo-1-methyl-1H-indol-3-yl)-4-(furo[2,3-b]p...)
Show SMILES Cn1cc(C2=C(C(=O)NC2=O)c2coc3ncccc23)c2ccc(Br)cc12
Show InChI InChI=1S/C20H12BrN3O3/c1-24-8-13(11-5-4-10(21)7-15(11)24)16-17(19(26)23-18(16)25)14-9-27-20-12(14)3-2-6-22-20/h2-9H,1H3,(H,23,25,26)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.94E+3n/an/an/an/an/an/a



Zhejiang University of Technology



Assay Description
The test methods for GSK-3β, PKCE, JAK2, BRAF, IKK2 and Drak2 inhibitory activities were reported in Molecules; 18:5498-5516. The PKA kinase ass...


Chem Biol Drug Des 86: 746-52 (2015)


Article DOI: 10.1111/cbdd.12546
BindingDB Entry DOI: 10.7270/Q2K9369N
More data for this
Ligand-Target Pair