BDBM16666 2-oxo-N-[2-(4-sulfamoylphenyl)ethyl]-2H-chromene-3-carboxamide::4-(Coumarin-3-yl-carboxamidoethyl)benzenesulfonamide::aromatic sulfonamide compound 31

SMILES NS(=O)(=O)c1ccc(CCNC(=O)c2cc3ccccc3oc2=O)cc1

InChI Key InChIKey=HQMMKFBZUNKWAS-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 16666   

TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM16666(2-oxo-N-[2-(4-sulfamoylphenyl)ethyl]-2H-chromene-3...)
Affinity DataKi:  10nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5A, mitochondrial(Mus musculus (mouse))
Universita Degli Studi Di Firenze

LigandPNGBDBM16666(2-oxo-N-[2-(4-sulfamoylphenyl)ethyl]-2H-chromene-3...)
Affinity DataKi:  18nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM16666(2-oxo-N-[2-(4-sulfamoylphenyl)ethyl]-2H-chromene-3...)
Affinity DataKi:  66nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed