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BDBM166679 4-(7-(2-Morpholin-4-yl-ethoxyimino)-4,5,6,7-tetrahydrobenzo[d]isoxazol-3-yl)benzamide (21b)

SMILES: NC(=O)c1ccc(cc1)-c1noc2c1CCCC2=NOCCN1CCOCC1

InChI Key: InChIKey=BXJNAAGVAOOCQY-XLNRJJMWSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 166679   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Heat-shock protein 90 (Hsp90)


(Homo sapiens (Human))
BDBM166679
PNG
(4-(7-(2-Morpholin-4-yl-ethoxyimino)-4,5,6,7-tetrah...)
Show SMILES NC(=O)c1ccc(cc1)-c1noc2c1CCCC2=NOCCN1CCOCC1
Show InChI InChI=1S/C20H24N4O4/c21-20(25)15-6-4-14(5-7-15)18-16-2-1-3-17(19(16)28-23-18)22-27-13-10-24-8-11-26-12-9-24/h4-7H,1-3,8-13H2,(H2,21,25)/b22-17-
UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



University of Milano



Assay Description
The fluorescence polarization (FP) assay was performed as described in the reference (Bioorg Med Chem. 2010. 18:6031-6043).


Chem Biol Drug Des 86: 1030-5 (2015)


Article DOI: 10.1111/cbdd.12570
BindingDB Entry DOI: 10.7270/Q22806CD
More data for this
Ligand-Target Pair