BDBM167644 US9073922, 131::US9796708, Example 131

SMILES COc1ccc(F)cc1-c1ccnc2[nH]c(cc12)[C@H]1CC[C@@H](CC1)NCCCC(O)=O

InChI Key InChIKey=QRJCAHPPWSSSME-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 167644   

TargetCyclin-dependent kinase 9(Human)
Abbvie

US Patent
LigandPNGBDBM167644(US9073922, 131 | US9796708, Example 131)
Affinity DataIC50: 64nMAssay Description:CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Abbvie

US Patent
LigandPNGBDBM167644(US9073922, 131 | US9796708, Example 131)
Affinity DataIC50: 64nMAssay Description:CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent