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BDBM167939 1',5'-Dimethyl-2,2'-diphenyl-5-(phenylsulfonyl)-1'H,2H-[3,4'-bipyrazol]-3'(2'H)-one (19)

SMILES: Cc1c(-c2cc(nn2-c2ccccc2)S(=O)(=O)c2ccccc2)c(=O)n(-c2ccccc2)n1C

InChI Key: InChIKey=DBMXYALXKYPVEZ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 167939   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dipeptidyl peptidase-IV (DDP-4)


(Homo sapiens (Human))
BDBM167939
PNG
(1',5'-Dimethyl-2,2'-diphenyl-5-(phenyl...)
Show SMILES Cc1c(-c2cc(nn2-c2ccccc2)S(=O)(=O)c2ccccc2)c(=O)n(-c2ccccc2)n1C
Show InChI InChI=1S/C26H22N4O3S/c1-19-25(26(31)30(28(19)2)21-14-8-4-9-15-21)23-18-24(27-29(23)20-12-6-3-7-13-20)34(32,33)22-16-10-5-11-17-22/h3-18H,1-2H3
PDB

B.MOAD
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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.64E+3n/an/an/an/an/a25



Cairo University



Assay Description
A 200-ÁL reaction system containing DPP-IV (Sigma), a test compound, and 25 mmol/L HEPES buffer (containing 140 mmol/L NaCl, 1% BSA, and 80 mmol/L Mg...


Chem Biol Drug Des 86: 1292-303 (2015)


Article DOI: 10.1111/cbdd.12593
BindingDB Entry DOI: 10.7270/Q2M32THN
More data for this
Ligand-Target Pair