BDBM167957 1-(4-(2,4-Dimethylphenyl)piperazin-1-yl)-3-(quinazolin-4-yloxy)propan-2-ol (3m)

SMILES Cc1ccc(N2CCN(CC(O)COc3ncnc4ccccc34)CC2)c(C)c1

InChI Key InChIKey=XXURFXAKIUOJDN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 167957   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Nanjing University

LigandPNGBDBM167957(1-(4-(2,4-Dimethylphenyl)piperazin-1-yl)-3-(quinaz...)
Affinity DataIC50:  12.4nMpH: 7.2 T: 2°CAssay Description:VEGFR kinase assays were set up to assess the level of autophosphorylation based on DELFIA/Time-Resolved Fluorometry. 96-well plates were coated at r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Nanjing University

LigandPNGBDBM167957(1-(4-(2,4-Dimethylphenyl)piperazin-1-yl)-3-(quinaz...)
Affinity DataIC50:  102nMpH: 7.2 T: 2°CAssay Description:VEGFR kinase assays were set up to assess the level of autophosphorylation based on DELFIA/Time-Resolved Fluorometry. 96-well plates were coated at r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor 2(Homo sapiens (Human))
Nanjing University

LigandPNGBDBM167957(1-(4-(2,4-Dimethylphenyl)piperazin-1-yl)-3-(quinaz...)
Affinity DataIC50:  222nMpH: 7.2 T: 2°CAssay Description:VEGFR kinase assays were set up to assess the level of autophosphorylation based on DELFIA/Time-Resolved Fluorometry. 96-well plates were coated at r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Nanjing University

LigandPNGBDBM167957(1-(4-(2,4-Dimethylphenyl)piperazin-1-yl)-3-(quinaz...)
Affinity DataIC50:  395nMpH: 7.2 T: 2°CAssay Description:VEGFR kinase assays were set up to assess the level of autophosphorylation based on DELFIA/Time-Resolved Fluorometry. 96-well plates were coated at r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed