BDBM168 (4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-3-[(3-hydroxyphenyl)methyl]-1-(1H-indazol-5-ylmethyl)-1,3-diazepan-2-one::CHEMBL433136::Cyclic Urea::[4R-(4,5,6,7)]-Hexahydro-5,6-dihydroxy-1-[(3-hydroxyphenyl)methyl]-3-(1H-indazol-5-ylmethyl)-4,7-bis(phenylmethyl)-2H-1,3-diazepin-2-one
SMILES O[C@@H]1[C@@H](O)[C@@H](Cc2ccccc2)N(Cc2ccc3[nH]ncc3c2)C(=O)N(Cc2cccc(O)c2)[C@@H]1Cc1ccccc1
InChI Key InChIKey=HMBROJULWCDLQT-FYZVQMPESA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 168
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 0.0450nMAssay Description:Inhibitory activity against HIV proteaseMore data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals
Dupont Pharmaceuticals
Affinity DataKi: 0.0450nM ΔG°: -14.7kcal/molepH: 5.5 T: 2°CAssay Description:Ki values were determined with recombinant single-chain dimeric HIV protease and a fluorescent substrate. The use of single-chain dimeric protease a...More data for this Ligand-Target Pair