BDBM168436 US9675591, SKA-19

SMILES: c1cc2c(cc1SC(F)(F)F)sc(n2)N

InChI Key: InChIKey=PBRVVEXJMLEKMJ-UHFFFAOYSA-N

Data: 7 IC50  9 EC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 168436   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Small conductance calcium-activated potassium channel protein 1 (Human)	BDBM168436 (US9675591, SKA-19) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	7.35	25
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Small conductance calcium-activated potassium channel protein 2 (Rat)	BDBM168436 (US9675591, SKA-19) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.40E+4	n/a	n/a	7.35	25
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Small conductance calcium-activated potassium channel protein 3 (Human)	BDBM168436 (US9675591, SKA-19) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.50E+4	n/a	n/a	7.35	25
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Sodium channel protein type 1 subunit alpha (Human)	BDBM168436 (US9675591, SKA-19) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	6.90E+3	n/a	n/a	7.35	25
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Sodium channel protein type 2 subunit alpha (Human)	BDBM168436 (US9675591, SKA-19) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	7.90E+3	n/a	n/a	7.35	25
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Sodium channel protein type 3 subunit alpha (Human)	BDBM168436 (US9675591, SKA-19) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.20E+3	n/a	n/a	7.35	25
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Sodium channel protein type 4 subunit alpha (Human)	BDBM168436 (US9675591, SKA-19) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	4.50E+3	n/a	n/a	7.35	25
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Sodium channel protein type 5 subunit alpha (Human)	BDBM168436 (US9675591, SKA-19) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	5.80E+3	n/a	n/a	7.35	25
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Potassium voltage-gated channel subfamily B member 1 (Human)	BDBM168436 (US9675591, SKA-19) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.23E+4	n/a	n/a	7.35	25
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM168436 (US9675591, SKA-19) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C19 (Human)	BDBM168436 (US9675591, SKA-19) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM168436 (US9675591, SKA-19) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM168436 (US9675591, SKA-19) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Pteridine reductase 1 (Leishmania major)	BDBM168436 (US9675591, SKA-19) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 1A2 (Human)	BDBM168436 (US9675591, SKA-19) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM168436 (US9675591, SKA-19) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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