BDBM168618 US9079852, Table F, Compound 3

SMILES CS(=O)(=O)Nc1ccc(OC[C@@H](O)CN2CCN(CC2)c2ccc(Cl)cc2)cc1

InChI Key InChIKey=VDICSHQGASSQTF-IBGZPJMESA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 168618   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Emory University

US Patent
LigandPNGBDBM168618(US9079852, Table F, Compound 3)
Affinity DataKi:  553nMAssay Description:Compounds were evaluated for binding to the human ether-a-go-go potassium channel (hERG) expressed in HEK293 cells by displacement of 3[H]-astemizole...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Emory University

US Patent
LigandPNGBDBM168618(US9079852, Table F, Compound 3)
Affinity DataIC50:  350nMAssay Description:Binding to the rat alpha-1 adrenergic receptor in rat brain membranes was determined by displacement of 3[H]-prazosin (P. Greengrass and R. Bremner; ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent