BDBM169219 US9079866, 620::US9745328, Compound 620::US9884878, Compound 620

SMILES Nc1ccc(Oc2ccccc2-c2ccc(c(F)c2)-c2cnc(N)cn2)nc1

InChI Key InChIKey=BXJJBRDSNZYMNU-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 169219   

TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM169219(US9079866, 620 | US9745328, Compound 620 | US98848...)
Affinity DataKi:  1.90nMAssay Description:The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFlap endonuclease 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM169219(US9079866, 620 | US9745328, Compound 620 | US98848...)
Affinity DataKi:  1.90nMAssay Description:The FLAP binding assay is performed in HTRF format (homogeneous time resolved fluorescence). FLAP-containing membranes (1 μg/well final for huma...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM169219(US9079866, 620 | US9745328, Compound 620 | US98848...)
Affinity DataKi:  1.90nMAssay Description:The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...More data for this Ligand-Target Pair
In DepthDetails US Patent