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BDBM169547 US9675593, 200

SMILES: CC(C)c1cc(=O)n(cc1-c1ccc(F)cc1)-c1ccc(OC(F)(F)F)cc1

InChI Key: InChIKey=GZRBGGXROJLYET-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 169547   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Endothelin-1


(Homo sapiens (Human))
BDBM169547
PNG
(US9675593, 200)
Show SMILES CC(C)c1cc(=O)n(cc1-c1ccc(F)cc1)-c1ccc(OC(F)(F)F)cc1
Show InChI InChI=1S/C21H17F4NO2/c1-13(2)18-11-20(27)26(12-19(18)14-3-5-15(22)6-4-14)16-7-9-17(10-8-16)28-21(23,24)25/h3-13H,1-2H3
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UniProtKB/SwissProt
UniProtKB/TrEMBL

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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 1.25E+5n/an/an/an/a



SRMLSC

US Patent


Assay Description
Fibroblasts (primary human lung and dermal, HFL-1, 3T3 etc) are seeded in 96-well plates at ~15000 cells/well and serum starved for 0-48 hours. After...


US Patent US9675593 (2017)


BindingDB Entry DOI: 10.7270/Q2319T24
More data for this
Ligand-Target Pair