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BDBM169696 US9073940, 45

SMILES: O=C(N1CCOCC1)c1nn(CC2CCCO2)c-2c1CS(=O)(=O)c1ccccc-21

InChI Key: InChIKey=SIXTZFGHCLDOLA-UHFFFAOYNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 169696   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphoinositide 3-kinases (PI3K)


(Homo sapiens (Human))
BDBM169696
PNG
(US9073940, 45)
Show SMILES O=C(N1CCOCC1)c1nn(CC2CCCO2)c-2c1CS(=O)(=O)c1ccccc-21
Show InChI InChI=1/C20H23N3O5S/c24-20(22-7-10-27-11-8-22)18-16-13-29(25,26)17-6-2-1-5-15(17)19(16)23(21-18)12-14-4-3-9-28-14/h1-2,5-6,14H,3-4,7-13H2
PDB

GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 1.56E+3n/an/an/an/an/an/a



Merck Serono

US Patent


Assay Description
The efficacy of compounds of the invention in inhibiting the PI3K induced-lipid phosphorylation may be tested in the following binding assay. The ass...


US Patent US9073940 (2015)


BindingDB Entry DOI: 10.7270/Q2ZC81N2
More data for this
Ligand-Target Pair