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BDBM169835 US9073940, 184

SMILES: Cc1noc(C)c1-c1cccc(c1)-n1nc(C(=O)N2CCOCC2)c2CS(=O)(=O)c3ccccc3-c12

InChI Key: InChIKey=MWFGYPVIIVOLMX-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 169835   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphoinositide 3-kinases (PI3K)


(Homo sapiens (Human))
BDBM169835
PNG
(US9073940, 184)
Show SMILES Cc1noc(C)c1-c1cccc(c1)-n1nc(C(=O)N2CCOCC2)c2CS(=O)(=O)c3ccccc3-c12
Show InChI InChI=1S/C26H24N4O5S/c1-16-23(17(2)35-28-16)18-6-5-7-19(14-18)30-25-20-8-3-4-9-22(20)36(32,33)15-21(25)24(27-30)26(31)29-10-12-34-13-11-29/h3-9,14H,10-13,15H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 300n/an/an/an/an/an/a



MERCK SERONO SA

US Patent


Assay Description
The efficacy of compounds of the invention in inhibiting the PI3K induced-lipid phosphorylation may be tested in the following binding assay. The ass...


US Patent US9073940 (2015)


BindingDB Entry DOI: 10.7270/Q2ZC81N2
More data for this
Ligand-Target Pair