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BDBM169936 US9073940, 286

SMILES: O=C(N1CCOCC1)c1nn(C2CCN(CCn3cccn3)C2)c-2c1CS(=O)(=O)c1ccccc-21

InChI Key: InChIKey=QWRWABZPKBNWJW-UHFFFAOYNA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 169936   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphoinositide 3-kinases (PI3K)


(Homo sapiens (Human))
BDBM169936
PNG
(US9073940, 286)
Show SMILES O=C(N1CCOCC1)c1nn(C2CCN(CCn3cccn3)C2)c-2c1CS(=O)(=O)c1ccccc-21
Show InChI InChI=1/C24H28N6O4S/c31-24(28-12-14-34-15-13-28)22-20-17-35(32,33)21-5-2-1-4-19(21)23(20)30(26-22)18-6-9-27(16-18)10-11-29-8-3-7-25-29/h1-5,7-8,18H,6,9-17H2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 257n/an/an/an/an/an/a



MERCK SERONO SA

US Patent


Assay Description
The efficacy of compounds of the invention in inhibiting the PI3K induced-lipid phosphorylation may be tested in the following binding assay. The ass...


US Patent US9073940 (2015)


BindingDB Entry DOI: 10.7270/Q2ZC81N2
More data for this
Ligand-Target Pair