BDBM17016 (3Z)-4-methyl-3-(1H-pyrrol-2-ylmethylidene)-2,3-dihydro-1H-indol-2-one::CHEMBL85403::Indolinone based inhibitor, 1a

SMILES: Cc1cccc2NC(=O)\C(=C/c3ccc[nH]3)c12

InChI Key: InChIKey=IUMPCHAHZBLTKY-UHFFFAOYSA-N

Data: 7 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 17016   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
3-phosphoinositide-dependent protein kinase 1 (Human)	BDBM17016 (CHEMBL85403 | (3Z)-4-methyl-3-(1H-pyrrol-2-ylmethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	510	n/a	n/a	n/a	n/a	7.2	22
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Platelet-derived growth factor receptor beta (Human)	BDBM17016 (CHEMBL85403 | (3Z)-4-methyl-3-(1H-pyrrol-2-ylmethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Insulin-like growth factor 1 receptor (Human)	BDBM17016 (CHEMBL85403 | (3Z)-4-methyl-3-(1H-pyrrol-2-ylmethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Receptor tyrosine-protein kinase erbB-2 (Human)	BDBM17016 (CHEMBL85403 | (3Z)-4-methyl-3-(1H-pyrrol-2-ylmethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 1 (Mouse)	BDBM17016 (CHEMBL85403 | (3Z)-4-methyl-3-(1H-pyrrol-2-ylmethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM17016 (CHEMBL85403 | (3Z)-4-methyl-3-(1H-pyrrol-2-ylmethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Mouse)	BDBM17016 (CHEMBL85403 | (3Z)-4-methyl-3-(1H-pyrrol-2-ylmethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.09E+4	n/a	n/a	n/a	n/a	n/a	n/a
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