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BDBM170216 US9079902, 47

SMILES: CN(C)c1cccc(c1)-c1cn(C)c2cc(ccc12)S(=O)(=O)Nc1ncns1

InChI Key: InChIKey=YFTWJMJJNTUAPW-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 170216   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sodium channel protein type 5 subunit alpha


(Homo sapiens (Human))
BDBM170216
PNG
(US9079902, 47)
Show SMILES CN(C)c1cccc(c1)-c1cn(C)c2cc(ccc12)S(=O)(=O)Nc1ncns1
Show InChI InChI=1S/C19H19N5O2S2/c1-23(2)14-6-4-5-13(9-14)17-11-24(3)18-10-15(7-8-16(17)18)28(25,26)22-19-20-12-21-27-19/h4-12H,1-3H3,(H,20,21,22)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a>1.00E+4n/an/an/an/an/an/a



Amgen Inc

US Patent


Assay Description
293 cells stably transfected with either Nav 1.7 or with Nav 1.5 were recorded in population patch-clamp mode with the IonWorks® Quattro automated el...


US Patent US9079902 (2015)


BindingDB Entry DOI: 10.7270/Q2J67FPN
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM170216
PNG
(US9079902, 47)
Show SMILES CN(C)c1cccc(c1)-c1cn(C)c2cc(ccc12)S(=O)(=O)Nc1ncns1
Show InChI InChI=1S/C19H19N5O2S2/c1-23(2)14-6-4-5-13(9-14)17-11-24(3)18-10-15(7-8-16(17)18)28(25,26)22-19-20-12-21-27-19/h4-12H,1-3H3,(H,20,21,22)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 4.20E+3n/an/an/an/an/an/a



Amgen Inc

US Patent


Assay Description
293 cells stably transfected with either Nav 1.7 or with Nav 1.5 were recorded in population patch-clamp mode with the IonWorks® Quattro automated el...


US Patent US9079902 (2015)


BindingDB Entry DOI: 10.7270/Q2J67FPN
More data for this
Ligand-Target Pair