BDBM170374 US9079913, MI-319-35

SMILES CC(C)(C)C[C@H]1N[C@H]([C@H](c2cc(Cl)ccn2)[C@@]11C(=O)Nc2cc(Cl)c(F)cc12)C(=O)NCC[C@H](O)CO

InChI Key InChIKey=DDOZHOLPFKQAEQ-CRYDRMAXSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 170374   

TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
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US Patent
LigandPNGBDBM170374(US9079913, MI-319-35)
Affinity DataIC50: <1.00E+4nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In DepthDetails US Patent