BDBM170445 US9085531, 17

SMILES CN1CC(c2ccc3ccoc3c2)c2ccccc2C1

InChI Key InChIKey=FKCXCDFQELSYLK-UHFFFAOYSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 170445   

TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM170445(US9085531, 17)
Affinity DataKi:  5.20nMpH: 7.4Assay Description:In order to evaluate the relative affinity of the various compounds at the NE, DA and 5HT transporters, HEK293E cell lines were developed to express ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM170445(US9085531, 17)
Affinity DataKi:  7.5nMpH: 7.4Assay Description:In order to evaluate the relative affinity of the various compounds at the NE, DA and 5HT transporters, HEK293E cell lines were developed to express ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM170445(US9085531, 17)
Affinity DataKi:  254nMpH: 7.4Assay Description:In order to evaluate the relative affinity of the various compounds at the NE, DA and 5HT transporters, HEK293E cell lines were developed to express ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM170445(US9085531, 17)
Affinity DataIC50:  5.20nMAssay Description:Displacement of [3H]Nisoxetine from human NET expressed in HEK293E cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM170445(US9085531, 17)
Affinity DataIC50:  7.5nMAssay Description:Displacement of [3H]WIN 35,428 from human DAT expressed in HEK293E cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM170445(US9085531, 17)
Affinity DataIC50:  250nMAssay Description:Displacement of [3H]Citolapram from human SERT expressed in HEK293E cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed