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BDBM170508 US9675593, 330

SMILES: CC(C)Oc1ccc(cc1)-n1cc(ccc1=O)-c1ccc(cc1)S(N)(=O)=O

InChI Key: InChIKey=UUENWURYMHXRLW-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 170508   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Endothelin-1


(Homo sapiens (Human))
BDBM170508
PNG
(US9675593, 330)
Show SMILES CC(C)Oc1ccc(cc1)-n1cc(ccc1=O)-c1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C20H20N2O4S/c1-14(2)26-18-8-6-17(7-9-18)22-13-16(5-12-20(22)23)15-3-10-19(11-4-15)27(21,24)25/h3-14H,1-2H3,(H2,21,24,25)
UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>2.00E+5n/an/an/an/a



SRMLSC

US Patent


Assay Description
Fibroblasts (primary human lung and dermal, HFL-1, 3T3 etc) are seeded in 96-well plates at ~15000 cells/well and serum starved for 0-48 hours. After...


US Patent US9675593 (2017)


BindingDB Entry DOI: 10.7270/Q2319T24
More data for this
Ligand-Target Pair