BDBM17052 BX-912::N-{3-[(5-bromo-4-{[2-(1H-imidazol-4-yl)ethyl]amino}pyrimidin-2-yl)amino]phenyl}pyrrolidine-1-carboxamide

SMILES: Brc1cnc(Nc2cccc(NC(=O)N3CCCC3)c2)nc1NCCc1cnc[nH]1

InChI Key: InChIKey=DMMILYKXNCVKOJ-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 17052   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
3-phosphoinositide-dependent protein kinase 1 (Human)	BDBM17052 (N-{3-[(5-bromo-4-{[2-(1H-imidazol-4-yl)ethyl]amino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	12	n/a	n/a	n/a	n/a	7.2	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
MAP/microtubule affinity-regulating kinase 3 (Human)	BDBM17052 (N-{3-[(5-bromo-4-{[2-(1H-imidazol-4-yl)ethyl]amino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.33E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
MAP/microtubule affinity-regulating kinase 4 (Human)	BDBM17052 (N-{3-[(5-bromo-4-{[2-(1H-imidazol-4-yl)ethyl]amino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	338	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase TBK1 (Human)	BDBM17052 (N-{3-[(5-bromo-4-{[2-(1H-imidazol-4-yl)ethyl]amino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.33E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair