BDBM17053 BX-320::N-(3-{[5-bromo-2-({3-[(pyrrolidin-1-ylcarbonyl)amino]phenyl}amino)pyrimidin-4-yl]amino}propyl)-2,2-dimethylpropanediamide::N-{3-[(5-bromo-2-{[3-(pyrrolidin-1-ylcarbonylamino)phenyl]amino}pyrimidin-4-yl)amino]propyl}-2,2-dimethylpropanediamide

SMILES: CC(C)(C(=O)N)C(=O)NCCCNc1c(cnc(n1)Nc2cccc(c2)NC(=O)N3CCCC3)Br

InChI Key: InChIKey=ZNSULAZTNWFKEW-UHFFFAOYSA-N

Data: 5 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 17053   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
3-phosphoinositide-dependent protein kinase 1 (Human)	BDBM17053 (N-(3-{[5-bromo-2-({3-[(pyrrolidin-1-ylcarbonyl)ami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	39	n/a	n/a	n/a	n/a	7.2	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Human)	BDBM17053 (N-(3-{[5-bromo-2-({3-[(pyrrolidin-1-ylcarbonyl)ami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Human)	BDBM17053 (N-(3-{[5-bromo-2-({3-[(pyrrolidin-1-ylcarbonyl)ami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Human)	BDBM17053 (N-(3-{[5-bromo-2-({3-[(pyrrolidin-1-ylcarbonyl)ami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Human)	BDBM17053 (N-(3-{[5-bromo-2-({3-[(pyrrolidin-1-ylcarbonyl)ami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair