BDBM17054 (2S,3R,4R,6R,18R)-18-hydroxy-3-methoxy-2-methyl-4-(methylamino)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]nonacosa-8,10,12,14,19,21,23,25,27-nonaen-16-one::(5S,6R,7R,9R,16R)-16-hydroxy-6-methoxy-5-methyl-7-(methylamino)-6,7,8,9,15,16-hexahydro-5H,14H-5,9-epoxy-4b,9a,15-triazadibenzo[b,h]cyclonona[1,2,3,4-jkl]cyclopenta[e]-as-indacen-14-one::7-Hydroxystaurosporine::UCN-01

SMILES: CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4[C@@H](O)NC(=O)c4c4c5ccccc5n2c4c13

InChI Key:

Data: 4 KI  3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 17054   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
3-phosphoinositide-dependent protein kinase 1 [51-359] (Human)	BDBM17054 ((5S,6R,7R,9R,16R)-16-hydroxy-6-methoxy-5-methyl-7-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	7.5	30
TBA									Citation and Details
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3-phosphoinositide-dependent protein kinase 1 [51-359] (Human)	BDBM17054 ((5S,6R,7R,9R,16R)-16-hydroxy-6-methoxy-5-methyl-7-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6	n/a	n/a	n/a	n/a	7.5	30
TBA									Citation and Details
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Serine/threonine-protein kinase Chk1 (Human)	BDBM17054 ((5S,6R,7R,9R,16R)-16-hydroxy-6-methoxy-5-methyl-7-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk1 (Human)	BDBM17054 ((5S,6R,7R,9R,16R)-16-hydroxy-6-methoxy-5-methyl-7-...) Show SMILES Show InChI	GoogleScholar	UniChem		5.60	-11.7	n/a	n/a	n/a	n/a	n/a	7.4	37
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Cyclin-A2/Cyclin-dependent kinase 2 (Human)	BDBM17054 ((5S,6R,7R,9R,16R)-16-hydroxy-6-methoxy-5-methyl-7-...) Show SMILES Show InChI	GoogleScholar	UniChem		30	-10.2	n/a	n/a	n/a	n/a	n/a	7.4	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-A2/Cyclin-dependent kinase 1 (Human)	BDBM17054 ((5S,6R,7R,9R,16R)-16-hydroxy-6-methoxy-5-methyl-7-...) Show SMILES Show InChI	GoogleScholar	UniChem		95	-9.48	n/a	n/a	n/a	n/a	n/a	7.4	22
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Cyclin-dependent kinase 4/G1/S-specific cyclin-D1 (Human)	BDBM17054 ((5S,6R,7R,9R,16R)-16-hydroxy-6-methoxy-5-methyl-7-...) Show SMILES Show InChI	GoogleScholar	UniChem		3.60E+3	-7.55	n/a	n/a	n/a	n/a	n/a	7.5	30
TBA									Citation and Details
					More data for this Ligand-Target Pair