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BDBM170606 US9085555, 31

SMILES: N[C@H]1C[C@H](N(C1)C(=O)Nc1cn(C(N)=O)c2ccccc12)C(=O)NCc1cccc(c1)C(F)(F)F

InChI Key: InChIKey=QRSAMYWTHXJTGZ-FPOITTPVNA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 170606   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Factor D


(Homo sapiens (Human))
BDBM170606
PNG
(US9085555, 31)
Show SMILES N[C@H]1C[C@H](N(C1)C(=O)Nc1cn(C(N)=O)c2ccccc12)C(=O)NCc1cccc(c1)C(F)(F)F
Show InChI InChI=1/C23H23F3N6O3/c24-23(25,26)14-5-3-4-13(8-14)10-29-20(33)19-9-15(27)11-32(19)22(35)30-17-12-31(21(28)34)18-7-2-1-6-16(17)18/h1-8,12,15,19H,9-11,27H2,(H2,28,34)(H,29,33)(H,30,35)/t15-,19-/s2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 1.22E+4n/an/an/an/a7.525



NOVARTIS AG

US Patent


Assay Description
Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compound at vario...


US Patent US9085555 (2015)


BindingDB Entry DOI: 10.7270/Q2RN36MP
More data for this
Ligand-Target Pair