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BDBM170865 US9085555, 293

SMILES: NC(=O)n1cc(NC(=O)N2CCS[C@H]2C(=O)NCc2ccc(Cl)s2)c2ccccc12

InChI Key: InChIKey=ITHCBNLWVRRMCQ-AGDOHHJYNA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 170865   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Complement factor D


(Homo sapiens (Human))
BDBM170865
PNG
(US9085555, 293)
Show SMILES NC(=O)n1cc(NC(=O)N2CCS[C@H]2C(=O)NCc2ccc(Cl)s2)c2ccccc12
Show InChI InChI=1/C19H18ClN5O3S2/c20-15-6-5-11(30-15)9-22-16(26)17-24(7-8-29-17)19(28)23-13-10-25(18(21)27)14-4-2-1-3-12(13)14/h1-6,10,17H,7-9H2,(H2,21,27)(H,22,26)(H,23,28)/t17-/s2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 35n/an/an/an/a7.525



Novartis AG

US Patent


Assay Description
Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compound at vario...


US Patent US9085555 (2015)


BindingDB Entry DOI: 10.7270/Q2RN36MP
More data for this
Ligand-Target Pair