BDBM170985 US9085555, 415::US9085555, 431

SMILES N[C@@H]1[C@@H](F)CN([C@@H]1C(=O)NCc1cccc(Cl)c1F)C(=O)Nc1cn(C(N)=O)c2ccccc12

InChI Key InChIKey=MACUOYCTKRKOGS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 170985   

TargetComplement factor D(Human)
Novartis

US Patent
LigandPNGBDBM170985(US9085555, 431 | US9085555, 415)
Affinity DataIC50: 31nMpH: 7.5 T: 2°CAssay Description:Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compound at vario...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details
US Patent

TargetComplement factor D(Human)
Novartis

US Patent
LigandPNGBDBM170985(US9085555, 431 | US9085555, 415)
Affinity DataIC50: 48nMpH: 7.5 T: 2°CAssay Description:Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compound at vario...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details
US Patent