BDBM171272 1-(2-((1R,3S,5R)-3-(((R)-1-(3-Chloro-2-fluorophenyl)ethyl)carbamoyl)-2-azabicyclo[3.1.0]hexan-2-yl)-2-oxoethyl)-1H-pyrazolo[3,4-c]pyridine-3-carboxamide (6)::US9085555, 702

SMILES: C[C@H](c1cccc(c1F)Cl)NC(=O)[C@@H]2C[C@H]3C[C@H]3N2C(=O)Cn4c5cnccc5c(n4)C(=O)N

InChI Key: InChIKey=YAALCKJNOOFODD-UHFFFAOYSA-N

Data: 7 IC50  2 Kd

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 171272   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Complement factor D (Human)	BDBM171272 (1-(2-((1R,3S,5R)-3-(((R)-1-(3-Chloro-2-fluoropheny...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	7.5	25
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Complement factor D [24-253] (Human)	BDBM171272 (1-(2-((1R,3S,5R)-3-(((R)-1-(3-Chloro-2-fluoropheny...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	17	n/a	n/a	n/a	n/a	7.5	25
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Complement factor D [24-253] (Mouse)	BDBM171272 (1-(2-((1R,3S,5R)-3-(((R)-1-(3-Chloro-2-fluoropheny...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	860	n/a	n/a	n/a	n/a	7.5	25
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Complement factor D [24-253] (Human)	BDBM171272 (1-(2-((1R,3S,5R)-3-(((R)-1-(3-Chloro-2-fluoropheny...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	30	n/a	n/a	n/a	n/a	7.4	4
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Complement factor B [470-764] (Human)	BDBM171272 (1-(2-((1R,3S,5R)-3-(((R)-1-(3-Chloro-2-fluoropheny...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	7.4	4
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Kallikrein-7 [37-253,Y180R] (Human)	BDBM171272 (1-(2-((1R,3S,5R)-3-(((R)-1-(3-Chloro-2-fluoropheny...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	5.6	25
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Complement factor D [24-253] (Human)	BDBM171272 (1-(2-((1R,3S,5R)-3-(((R)-1-(3-Chloro-2-fluoropheny...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	6.03	n/a	n/a	n/a	7.4	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Complement factor D [24-253] (Human)	BDBM171272 (1-(2-((1R,3S,5R)-3-(((R)-1-(3-Chloro-2-fluoropheny...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	6.55	n/a	n/a	n/a	7.4	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Complement factor D (Human)	BDBM171272 (1-(2-((1R,3S,5R)-3-(((R)-1-(3-Chloro-2-fluoropheny...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair