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BDBM1713 US8470837, 9

SMILES: Cc1c(Nc2ccc(Br)cc2F)c2c(ncn(C[C@H](O)CO)c2=O)n(C)c1=O

InChI Key: InChIKey=OREFHJWLWMSGOW-NSHDSACASA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 1713   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dual specificity mitogen-activated protein kinase kinase 1


(Homo sapiens (human))
BDBM1713
PNG
(US8470837, 9)
Show SMILES Cc1c(Nc2ccc(Br)cc2F)c2c(ncn(C[C@H](O)CO)c2=O)n(C)c1=O
Show InChI InChI=1S/C18H18BrFN4O4/c1-9-15(22-13-4-3-10(19)5-12(13)20)14-16(23(2)17(9)27)21-8-24(18(14)28)6-11(26)7-25/h3-5,8,11,22,25-26H,6-7H2,1-2H3/t11-/m0/s1
PDB
MMDB

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

n/an/a>16n/an/an/an/an/an/a



Takeda Pharmaceutical Company Limted

US Patent


Assay Description
Reaction product is determined quantitatively by fluorescent polarization using progressive IMAP beads from Molecular Devices.


US Patent US8470837 (2013)


BindingDB Entry DOI: 10.7270/Q2N29VJ4
More data for this
Ligand-Target Pair