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BDBM1713 US8470837, 9

SMILES: Cc1c(Nc2ccc(Br)cc2F)c2c(ncn(C[C@H](O)CO)c2=O)n(C)c1=O

InChI Key: InChIKey=OREFHJWLWMSGOW-NSHDSACASA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 1713   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dual specificity mitogen-activated protein kinase kinase 1


(Homo sapiens (Human))
BDBM1713
PNG
(US8470837, 9)
Show SMILES Cc1c(Nc2ccc(Br)cc2F)c2c(ncn(C[C@H](O)CO)c2=O)n(C)c1=O
Show InChI InChI=1S/C18H18BrFN4O4/c1-9-15(22-13-4-3-10(19)5-12(13)20)14-16(23(2)17(9)27)21-8-24(18(14)28)6-11(26)7-25/h3-5,8,11,22,25-26H,6-7H2,1-2H3/t11-/m0/s1
PDB
MMDB

GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a>16n/an/an/an/a7.325



Takeda Pharmaceutical Co., Ltd

US Patent


Assay Description
Reaction product is determined quantitatively by fluorescent polarization using progressive IMAP beads from Molecular Devices.


US Patent US8470837 (2013)


BindingDB Entry DOI: 10.7270/Q2N29VJ4
More data for this
Ligand-Target Pair