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BDBM171307 US9085555, 737

SMILES: C[C@]12C[C@H]1N([C@@H](C2)C(=O)Nc1cccc(OC(F)(F)F)c1F)C(=O)Cn1nc(C(N)=O)c2ccccc12

InChI Key: InChIKey=COWZRFAWYWMWCY-JCEJCQQGSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 171307   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Factor D


(Homo sapiens (Human))
BDBM171307
PNG
(US9085555, 737)
Show SMILES C[C@]12C[C@H]1N([C@@H](C2)C(=O)Nc1cccc(OC(F)(F)F)c1F)C(=O)Cn1nc(C(N)=O)c2ccccc12
Show InChI InChI=1S/C24H21F4N5O4/c1-23-9-15(22(36)30-13-6-4-8-16(19(13)25)37-24(26,27)28)33(17(23)10-23)18(34)11-32-14-7-3-2-5-12(14)20(31-32)21(29)35/h2-8,15,17H,9-11H2,1H3,(H2,29,35)(H,30,36)/t15-,17+,23-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 36n/an/an/an/a7.525



NOVARTIS AG

US Patent


Assay Description
Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compound at vario...


US Patent US9085555 (2015)


BindingDB Entry DOI: 10.7270/Q2RN36MP
More data for this
Ligand-Target Pair