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BDBM171819 US9085576, 320

SMILES: C[C@]1([C@H]2C[C@H]2OC(=N1)N)c3cc(ccc3F)NC(=O)c4cnc(cn4)OC

InChI Key: InChIKey=LUOFRFUNXXGHFC-UHFFFAOYSA-N

Data: 4 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 171819
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Beta-secretase 1 (Human)	BDBM171819 (US9085576, 320) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	56.5	n/a	n/a	n/a	n/a	4.2	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Cathepsin D (Human)	BDBM171819 (US9085576, 320) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>4.00E+5	n/a	n/a	n/a	n/a	3.5	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Beta-secretase 1 (Human)	BDBM171819 (US9085576, 320) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Beta-secretase 1 (Human)	BDBM171819 (US9085576, 320) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	81	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair