BDBM171833 US9085584, 3
SMILES Cc1ccc2nc(C)c3nnc(-c4cccc(O)c4)n3c2n1
InChI Key InChIKey=OFBDYPOKLBUABM-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 171833
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 411nMT: 2°CAssay Description:For assessing activity of compounds on PDE10 inhibition, the following modifications of the protocol described below are applied: protein amount: ...More data for this Ligand-Target Pair
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 155nMT: 2°CAssay Description:For all experiments the Phosphodiesterase [3H]cAMP SPA Enzyme Assay (TRKQ7090, GE Healthcare Europe GmbH) were used. The enzymatic activity of the PD...More data for this Ligand-Target Pair