BDBM171833 US9085584, 3

SMILES Cc1ccc2nc(C)c3nnc(-c4cccc(O)c4)n3c2n1

InChI Key InChIKey=OFBDYPOKLBUABM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 171833   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM171833(US9085584, 3)
Affinity DataIC50:  411nMT: 2°CAssay Description:For assessing activity of compounds on PDE10 inhibition, the following modifications of the protocol described below are applied: protein amount: ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM171833(US9085584, 3)
Affinity DataIC50:  155nMT: 2°CAssay Description:For all experiments the Phosphodiesterase [3H]cAMP SPA Enzyme Assay (TRKQ7090, GE Healthcare Europe GmbH) were used. The enzymatic activity of the PD...More data for this Ligand-Target Pair
In DepthDetails US Patent