BDBM171870 US9085584, 37

SMILES Cc1nc2cccnc2n2c(nnc12)-c1cc(OCC2(C)COC2)ccc1Cl

InChI Key InChIKey=WZSRDUWBKLPJCS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 171870   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM171870(US9085584, 37)
Affinity DataIC50: 171nMT: 2°CAssay Description:For all experiments the Phosphodiesterase [3H]cAMP SPA Enzyme Assay (TRKQ7090, GE Healthcare Europe GmbH) were used. The enzymatic activity of the PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
US Patent

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM171870(US9085584, 37)
Affinity DataIC50: 3.08E+3nMT: 2°CAssay Description:For assessing activity of compounds on PDE10 inhibition, the following modifications of the protocol described below are applied: protein amount: ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
US Patent