BDBM172038 BDBM190183::US10155002, Compound 44::US10647700, Compound EPZ6438::US11052093, Compound 143::US11535629, Compound Control A::US9090562, 143::US9090562, 44::US9394283, 1

SMILES: CCN(C1CCOCC1)c1cc(cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)-c1ccc(CN2CCOCC2)cc1

InChI Key: InChIKey=NSQSAUGJQHDYNO-UHFFFAOYSA-N

Data: 3 KI  47 IC50  2 Kd  10 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 77 hits for monomerid = 172038   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone-lysine N-methyltransferase EZH2 (Human)	BDBM172038 (US10647700, Compound EPZ6438 | BDBM190183 | US1015...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Human)	BDBM172038 (US10647700, Compound EPZ6438 | BDBM190183 | US1015...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Human)	BDBM172038 (US10647700, Compound EPZ6438 | BDBM190183 | US1015...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Human)	BDBM172038 (US10647700, Compound EPZ6438 | BDBM190183 | US1015...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	9.10	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Human)	BDBM172038 (US10647700, Compound EPZ6438 | BDBM190183 | US1015...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Human)	BDBM172038 (US10647700, Compound EPZ6438 | BDBM190183 | US1015...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Human)	BDBM172038 (US10647700, Compound EPZ6438 | BDBM190183 | US1015...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Human)	BDBM172038 (US10647700, Compound EPZ6438 | BDBM190183 | US1015...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH1 (Human)	BDBM172038 (US10647700, Compound EPZ6438 | BDBM190183 | US1015...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	392	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Human)	BDBM172038 (US10647700, Compound EPZ6438 | BDBM190183 | US1015...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Human)	BDBM172038 (US10647700, Compound EPZ6438 | BDBM190183 | US1015...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Human)	BDBM172038 (US10647700, Compound EPZ6438 | BDBM190183 | US1015...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Human)	BDBM172038 (US10647700, Compound EPZ6438 | BDBM190183 | US1015...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Human)	BDBM172038 (US10647700, Compound EPZ6438 | BDBM190183 | US1015...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Human)	BDBM172038 (US10647700, Compound EPZ6438 | BDBM190183 | US1015...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Human)	BDBM172038 (US10647700, Compound EPZ6438 | BDBM190183 | US1015...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Human)	BDBM172038 (US10647700, Compound EPZ6438 | BDBM190183 | US1015...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Human)	BDBM172038 (US10647700, Compound EPZ6438 | BDBM190183 | US1015...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	64	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Human)	BDBM172038 (US10647700, Compound EPZ6438 | BDBM190183 | US1015...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Human)	BDBM172038 (US10647700, Compound EPZ6438 | BDBM190183 | US1015...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polycomb protein EED (Human)	BDBM172038 (US10647700, Compound EPZ6438 | BDBM190183 | US1015...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polycomb protein EED (Human)	BDBM172038 (US10647700, Compound EPZ6438 | BDBM190183 | US1015...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Human)	BDBM172038 (US10647700, Compound EPZ6438 | BDBM190183 | US1015...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Human)	BDBM172038 (US10647700, Compound EPZ6438 | BDBM190183 | US1015...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Human)	BDBM172038 (US10647700, Compound EPZ6438 | BDBM190183 | US1015...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Human)	BDBM172038 (US10647700, Compound EPZ6438 | BDBM190183 | US1015...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Human)	BDBM172038 (US10647700, Compound EPZ6438 | BDBM190183 | US1015...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Human)	BDBM172038 (US10647700, Compound EPZ6438 | BDBM190183 | US1015...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Human)	BDBM172038 (US10647700, Compound EPZ6438 | BDBM190183 | US1015...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	62	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Human)	BDBM172038 (US10647700, Compound EPZ6438 | BDBM190183 | US1015...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Human)	BDBM172038 (US10647700, Compound EPZ6438 | BDBM190183 | US1015...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Human)	BDBM172038 (US10647700, Compound EPZ6438 | BDBM190183 | US1015...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH1 (Human)	BDBM172038 (US10647700, Compound EPZ6438 | BDBM190183 | US1015...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	93	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Human)	BDBM172038 (US10647700, Compound EPZ6438 | BDBM190183 | US1015...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Human)	BDBM172038 (US10647700, Compound EPZ6438 | BDBM190183 | US1015...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH1 (Human)	BDBM172038 (US10647700, Compound EPZ6438 | BDBM190183 | US1015...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.17E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Human)	BDBM172038 (US10647700, Compound EPZ6438 | BDBM190183 | US1015...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 [A677G] (Human)	BDBM172038 (US10647700, Compound EPZ6438 | BDBM190183 | US1015...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Human)	BDBM172038 (US10647700, Compound EPZ6438 | BDBM190183 | US1015...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	64	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 [Y641F] (Human)	BDBM172038 (US10647700, Compound EPZ6438 | BDBM190183 | US1015...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	655	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Human)	BDBM172038 (US10647700, Compound EPZ6438 | BDBM190183 | US1015...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 [Y641F] (Human)	BDBM172038 (US10647700, Compound EPZ6438 | BDBM190183 | US1015...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	11.1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Human)	BDBM172038 (US10647700, Compound EPZ6438 | BDBM190183 | US1015...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 [Y641F] (Human)	BDBM172038 (US10647700, Compound EPZ6438 | BDBM190183 | US1015...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	219	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Human)	BDBM172038 (US10647700, Compound EPZ6438 | BDBM190183 | US1015...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	11.1	n/a	n/a	n/a	n/a	n/a	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Human)	BDBM172038 (US10647700, Compound EPZ6438 | BDBM190183 | US1015...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13.0	n/a	n/a	n/a	n/a	n/a	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 [A687V] (Human)	BDBM172038 (US10647700, Compound EPZ6438 | BDBM190183 | US1015...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Human)	BDBM172038 (US10647700, Compound EPZ6438 | BDBM190183 | US1015...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.07	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 [Y641F] (Human)	BDBM172038 (US10647700, Compound EPZ6438 | BDBM190183 | US1015...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	11.1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Human)	BDBM172038 (US10647700, Compound EPZ6438 | BDBM190183 | US1015...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair