BDBM172596 US9675593, 674

SMILES Cc1nc2c(c(cn(-c3ccc(OC(F)(F)F)cc3)c2=O)-c2cnn(C)c2)n1C

InChI Key InChIKey=MYIPIJGKDBVDIT-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 172596   

TargetEndothelin-1(Human)
Intermune

US Patent
LigandPNGBDBM172596(US9675593, 674)
Affinity DataEC50:  1.25E+5nMAssay Description:Fibroblasts (primary human lung and dermal, HFL-1, 3T3 etc) are seeded in 96-well plates at ~15000 cells/well and serum starved for 0-48 hours. After...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2018
Entry Details
US Patent