BDBM172651 US9090628, 311::US9090628, 319::US9090628, 321::US9090628, 322

SMILES CC(C)n1nc(C)nc1-c1cn2CCOc3cc(ccc3-c2n1)N1CCCC1C1CCCN(C)C1

InChI Key InChIKey=XUSKNOLOZFGDSE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 172651   

LigandPNGBDBM172651(US9090628, 322 | US9090628, 321 | US9090628, 319 |...)
Affinity DataIC50: 1.35nMpH: 7.5Assay Description:PI3K enzymatic activity was assayed by measuring the amount of product phosphatidylinositol 3,4,5-phosphate (PIP3) formed from substrate 4,5 phosphat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
US Patent

LigandPNGBDBM172651(US9090628, 322 | US9090628, 321 | US9090628, 319 |...)
Affinity DataIC50: 2.52nMpH: 7.5Assay Description:PI3K enzymatic activity was assayed by measuring the amount of product phosphatidylinositol 3,4,5-phosphate (PIP3) formed from substrate 4,5 phosphat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
US Patent

LigandPNGBDBM172651(US9090628, 322 | US9090628, 321 | US9090628, 319 |...)
Affinity DataIC50: 2.81nMpH: 7.5Assay Description:PI3K enzymatic activity was assayed by measuring the amount of product phosphatidylinositol 3,4,5-phosphate (PIP3) formed from substrate 4,5 phosphat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
US Patent

LigandPNGBDBM172651(US9090628, 322 | US9090628, 321 | US9090628, 319 |...)
Affinity DataIC50: 5.68nMpH: 7.5Assay Description:PI3K enzymatic activity was assayed by measuring the amount of product phosphatidylinositol 3,4,5-phosphate (PIP3) formed from substrate 4,5 phosphat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
US Patent