BDBM172696 US9090628, 356::US9090628, 368

SMILES COc1cc2OCCn3cc(nc3-c2cc1[C@@H](C)N1CCN(CC1)C(C)(C)C)-c1nc(C)nn1C(C)C

InChI Key InChIKey=PGCKRQJTWQLDQT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 172696   

LigandPNGBDBM172696(US9090628, 368 | US9090628, 356)
Affinity DataIC50: 1.05nMpH: 7.5Assay Description:PI3K enzymatic activity was assayed by measuring the amount of product phosphatidylinositol 3,4,5-phosphate (PIP3) formed from substrate 4,5 phosphat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
US Patent

LigandPNGBDBM172696(US9090628, 368 | US9090628, 356)
Affinity DataIC50: 1.06nMpH: 7.5Assay Description:PI3K enzymatic activity was assayed by measuring the amount of product phosphatidylinositol 3,4,5-phosphate (PIP3) formed from substrate 4,5 phosphat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
US Patent