BDBM17283 (2S)-3-(7-carbamimidoylnaphthalen-2-yl)-2-(4-{[(3S)-1-ethanimidoylpyrrolidin-3-yl]oxy}phenyl)propanoic acid::CHEMBL19902::DX-9065a
SMILES CC(=N)N1CC[C@@H](C1)Oc1ccc(cc1)[C@H](Cc1ccc2ccc(cc2c1)C(N)=N)C(O)=O
InChI Key InChIKey=AGRCGQSFFMCBRE-ZEQRLZLVSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 28 hits for monomerid = 17283
Affinity DataKi: 20nM ΔG°: -10.4kcal/molepH: 7.5 T: 2°CAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataKi: 22nMAssay Description:Compound was tested for inhibition activity against factor Xa (FXa)More data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:In vitro inhibition of human coagulation factor Xa (Xa) in a purified enzyme system.More data for this Ligand-Target Pair
Affinity DataKi: 41nMAssay Description:Inhibition of human factor 10a by Lineweaver-Burk plotMore data for this Ligand-Target Pair
Affinity DataKi: 41nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
Affinity DataKi: 41nMAssay Description:Binding affinity against Coagulation factor XChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 41nMAssay Description:Inhibition of factor 10a in human plasmaMore data for this Ligand-Target Pair
Affinity DataKi: 190nMAssay Description:Compound was tested for inhibition activity against bovine trypsin.More data for this Ligand-Target Pair
Affinity DataKi: 200nM ΔG°: -9.04kcal/molepH: 7.5 T: 2°CAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
Affinity DataKi: 620nMAssay Description:Binding affinity against TrypsinChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+3nMAssay Description:Compound was tested for inhibition activity against human thrombin (FIIa)More data for this Ligand-Target Pair
Affinity DataKi: 2.10E+4nMAssay Description:Inhibition of human recombinant tissue plasminogen activator by Lineweaver-Burk plotMore data for this Ligand-Target Pair
Affinity DataKi: 2.30E+4nMAssay Description:Inhibition of human plasmin by Lineweaver-Burk plotMore data for this Ligand-Target Pair
Affinity DataKi: >2.00E+6nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: >2.00E+6nMAssay Description:Binding affinity against Thrombin.Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: >2.00E+6nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
Affinity DataKi: >2.00E+6nMAssay Description:Inhibition of human thrombin by Lineweaver-Burk plotMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+6nMAssay Description:In vitro evaluation for the concentration needed for inhibiting thrombin by 50%More data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Compound was tested for the inhibition of serine protease factor Xa enzyme.More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+6nMAssay Description:Inhibitory Activity against ThrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibitory Activity against human Coagulation factor XMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:In vitro evaluation for the concentration needed for inhibiting factor Xa by 50%More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair