BDBM17284 2-{[2-(5-carbamimidoyl-2-hydroxyphenoxy)-3,5-difluoro-6-[3-(1-methyl-4,5-dihydro-1H-imidazol-2-yl)phenoxy]pyridin-4-yl](methyl)amino}acetic acid::CHEMBL73193::CI-1031::ZK-807834

SMILES: [H]/N=C(\c1ccc(c(c1)Oc2c(c(c(c(n2)Oc3cccc(c3)C4=NCCN4C)F)N(C)CC(=O)O)F)O)/N

InChI Key: InChIKey=NPNSVNGQJGRSNR-UHFFFAOYSA-N

Data: 9 KI

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 17284   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Human)	BDBM17284 (2-{[2-(5-carbamimidoyl-2-hydroxyphenoxy)-3,5-diflu...) Show SMILES Show InChI	GoogleScholar	UniChem		0.110	-13.4	n/a	n/a	n/a	n/a	n/a	7.5	22
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Coagulation factor X (Human)	BDBM17284 (2-{[2-(5-carbamimidoyl-2-hydroxyphenoxy)-3,5-diflu...) Show SMILES Show InChI	GoogleScholar	UniChem		0.110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Coagulation factor X (Human)	BDBM17284 (2-{[2-(5-carbamimidoyl-2-hydroxyphenoxy)-3,5-diflu...) Show SMILES Show InChI	GoogleScholar	UniChem		0.110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Coagulation factor X (Human)	BDBM17284 (2-{[2-(5-carbamimidoyl-2-hydroxyphenoxy)-3,5-diflu...) Show SMILES Show InChI	GoogleScholar	UniChem		0.110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Serine protease 1 (Bovine)	BDBM17284 (2-{[2-(5-carbamimidoyl-2-hydroxyphenoxy)-3,5-diflu...) Show SMILES Show InChI	GoogleScholar	UniChem		280	-8.84	n/a	n/a	n/a	n/a	n/a	7.5	22
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Serine protease 1 (Bovine)	BDBM17284 (2-{[2-(5-carbamimidoyl-2-hydroxyphenoxy)-3,5-diflu...) Show SMILES Show InChI	GoogleScholar	UniChem		280	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Serine protease 1 (Bovine)	BDBM17284 (2-{[2-(5-carbamimidoyl-2-hydroxyphenoxy)-3,5-diflu...) Show SMILES Show InChI	GoogleScholar	UniChem		280	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Prothrombin (Human)	BDBM17284 (2-{[2-(5-carbamimidoyl-2-hydroxyphenoxy)-3,5-diflu...) Show SMILES Show InChI	GoogleScholar	UniChem		2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Prothrombin (Human)	BDBM17284 (2-{[2-(5-carbamimidoyl-2-hydroxyphenoxy)-3,5-diflu...) Show SMILES Show InChI	GoogleScholar	UniChem		2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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