BDBM172917 US9096579, 19

SMILES CN(C)C(=O)c1cc2cc(Nc3nccc(n3)-c3cn(C)cn3)cc(-c3cnn(C)c3)c2[nH]1

InChI Key InChIKey=JNUCTSGRAQTLNW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 172917   

TargetTyrosine-protein kinase SYK(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM172917(US9096579, 19)
Affinity DataIC50: 8.10nMAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM172917(US9096579, 19)
Affinity DataIC50: 10.2nMAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent