BDBM173538 (E)-N'-(2-hydroxybenzylidene)-1H-indole-2-carbohydrazide (10)

SMILES Oc1ccccc1\C=N\NC(=O)c1cc2ccccc2[nH]1

InChI Key InChIKey=RWGDZRVPFFCMMX-LICLKQGHSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 173538   

TargetProbable maltase-glucoamylase 2(Homo sapiens)
Babasaheb Bhimrao Ambedkar University (A Central University)

Curated by ChEMBL
LigandPNGBDBM173538((E)-N'-(2-hydroxybenzylidene)-1H-indole-2-carb...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of alpha-glucosidase (unknown origin) using pNPG as substrate preincubated for 10 mins followed by substrate addition measured after 30 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOligo-1,6-glucosidase IMA1(Saccharomyces cerevisiae S288c (Baker's yeast))
Universiti Teknologi Mara (Uitm)

LigandPNGBDBM173538((E)-N'-(2-hydroxybenzylidene)-1H-indole-2-carb...)
Affinity DataIC50:  4.26E+4nMAssay Description:The 135 µL of 50 mM phosphate saline buffer pH (6.8) was added in the 96-well plate and 20 µL of test sample with 70% DMSO added into the wells. The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed