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BDBM173631 US9102591, 2-Methyl-N-(1-pyridin-3-yl-cyclopentylmethyl)-benzamide::US9649308, 2-Methyl-N-(1-pyridin-3-yl-cyclopentylmethyl)-benzamide

SMILES: Cc1ccccc1C(=O)NCC1(CCCC1)c1cccnc1

InChI Key: InChIKey=YZSHNJLAVFLXCZ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB:
Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 173631   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
P2X purinoceptor 7


(Homo sapiens (Human))
BDBM173631
PNG
(US9102591, 2-Methyl-N-(1-pyridin-3-yl-cyclopentylm...)
Show SMILES Cc1ccccc1C(=O)NCC1(CCCC1)c1cccnc1
Show InChI InChI=1S/C19H22N2O/c1-15-7-2-3-9-17(15)18(22)21-14-19(10-4-5-11-19)16-8-6-12-20-13-16/h2-3,6-9,12-13H,4-5,10-11,14H2,1H3,(H,21,22)
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PC cid
PC sid
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Similars

US Patent
n/an/a 3.60E+3n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...


US Patent US9649308 (2017)


BindingDB Entry DOI: 10.7270/Q2BG2R29
More data for this
Ligand-Target Pair
P2X purinoceptor 7


(Homo sapiens (Human))
BDBM173631
PNG
(US9102591, 2-Methyl-N-(1-pyridin-3-yl-cyclopentylm...)
Show SMILES Cc1ccccc1C(=O)NCC1(CCCC1)c1cccnc1
Show InChI InChI=1S/C19H22N2O/c1-15-7-2-3-9-17(15)18(22)21-14-19(10-4-5-11-19)16-8-6-12-20-13-16/h2-3,6-9,12-13H,4-5,10-11,14H2,1H3,(H,21,22)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 3.60E+3n/an/an/an/a7.425



H. Lundbeck A/S

US Patent


Assay Description
Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...


US Patent US9102591 (2015)


BindingDB Entry DOI: 10.7270/Q2028Q92
More data for this
Ligand-Target Pair