BDBM173658 US9102591, N-((4,4-difluoro-1-(6-fluoropyridin-3-yl)cyclohexyl)methyl)-2-fluoro-3-methylbenzamide::US9649308, N-((4,4-difluoro-1-(6-fluoropyridin-3-yl)cyclohexyl)methyl)-2-fluoro-3-methylbenzamide

SMILES Cc1cccc(C(=O)NCC2(CCC(F)(F)CC2)c2ccc(F)nc2)c1F

InChI Key InChIKey=GCZVYZQPJHAFRR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 173658   

TargetP2X purinoceptor 7(Human)
H. Lundbeck

US Patent
LigandPNGBDBM173658(US9102591, N-((4,4-difluoro-1-(6-fluoropyridin-3-y...)
Affinity DataIC50: 78nMAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2019
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
H. Lundbeck

US Patent
LigandPNGBDBM173658(US9102591, N-((4,4-difluoro-1-(6-fluoropyridin-3-y...)
Affinity DataIC50: 78nMpH: 7.4 T: 2°CAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
US Patent