BDBM173739 US9102591, (+)2,6-dichloro-N-[3-cyclopropyl-2-[6-(trifluoromethyl)-3-pyridyl]propyl]benzamide::US9102591, (-)2,6-dichloro-N-[3-cyclopropyl-2-[6-(trifluoromethyl)-3-pyridyl]propyl]benzamide::US9102591, 2,6-dichloro-N-(3-cyclopropyl-2-(6-(trifluoromethyl)pyridin-3-yl)propyl)benzamide::US9649308, (+)2,6-dichloro-N-[3-cyclopropyl-2-[6-(trifluoromethyl)-3-pyridyl]propyl]benzamide

SMILES FC(F)(F)c1ccc(cn1)C(CNC(=O)c1c(Cl)cccc1Cl)CC1CC1

InChI Key InChIKey=HGZIMQXJAFSFJC-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 173739   

TargetP2X purinoceptor 7(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM173739(US9102591, (+)2,6-dichloro-N-[3-cyclopropyl-2-[6-(...)
Affinity DataIC50:  0.710nMpH: 7.4 T: 2°CAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM173739(US9102591, (+)2,6-dichloro-N-[3-cyclopropyl-2-[6-(...)
Affinity DataIC50:  1.20nMpH: 7.4 T: 2°CAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM173739(US9102591, (+)2,6-dichloro-N-[3-cyclopropyl-2-[6-(...)
Affinity DataIC50:  0.890nMAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM173739(US9102591, (+)2,6-dichloro-N-[3-cyclopropyl-2-[6-(...)
Affinity DataIC50:  0.710nMAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM173739(US9102591, (+)2,6-dichloro-N-[3-cyclopropyl-2-[6-(...)
Affinity DataIC50:  1.20nMAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM173739(US9102591, (+)2,6-dichloro-N-[3-cyclopropyl-2-[6-(...)
Affinity DataIC50:  0.890nMpH: 7.4 T: 2°CAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In DepthDetails US Patent